Name:
Disseminated Intravascular Coagulation
Other Name(s):
Acronym(s):
Severity:
Genetic:
Idiopathic:
Predisposed Breeds:
Onset Age:
Overview
Disseminated intravascular coagulation (DIC), also known as consumptive coagulopathy, is a condition in dogs. It involves the excessive formation of blood clots in the small blood vessels throughout the body. This leads to the depletion of clotting factors and platelets, potentially resulting in widespread bleeding. DIC is often secondary to severe systemic illnesses. Though relatively uncommon, it poses a life-threatening risk and demands immediate veterinary care.
Causes
Primary causes of DIC include severe systemic illnesses like sepsis, severe trauma, heatstroke, or pancreatitis. These conditions can trigger the coagulation cascade, leading to the excessive clotting characteristic of DIC.
Secondary causes involve certain types of cancer, such as hemangiosarcoma or leukemia, severe infections, and immune-mediated diseases. These conditions can also start the coagulation process, resulting in DIC.
Other causes include toxins such as snake venom and certain medications. These substances can further complicate the dog’s condition by contributing to the development of DIC, highlighting the importance of prompt veterinary attention.
Predisposed Breeds
There are no specific breeds predisposed to disseminated intravascular coagulation.
Symptoms
Dogs with DIC may show primary symptoms, such as excessive bleeding from minor injuries or spontaneous bleeding from the gums or nose. Blood in the urine or stool is also common, suggesting abnormal clotting processes.
Secondary symptoms may include lethargy, pale gums, and rapid breathing. These signs point to underlying organ dysfunction, such as jaundice, which requires immediate medical evaluation.
Other symptoms can involve signs of shock, like a weak pulse and cold extremities. Neurological signs may appear if bleeding occurs in the brain, which can further complicate the prognosis.
Disseminated intravascular coagulation symptoms include:
- Excessive bleeding
- Spontaneous bleeding
- Blood in urine/stool
- Lethargy
- Pale gums
- Rapid breathing
- Signs of organ dysfunction
Diagnosis
Diagnosing DIC involves a thorough clinical examination by a veterinarian. Blood tests typically reveal low platelet counts, prolonged clotting times, and evidence of organ dysfunction, which indicate DIC.
It is essential to differentiate diagnosing disseminated intravascular from other conditions, such as immune-mediated thrombocytopenia, heat stroke, and sepsis. Correct diagnosis ensures the appropriate treatment plan is put into practice promptly.
Imaging tests and additional diagnostics may assess the extent of organ involvement and to monitor the dog’s response to treatment. Early identification of clinical signs is important for successful intervention.
Treatment
Treatment of DIC focuses on addressing the underlying cause while providing supportive care. Fluid therapy and blood transfusions are common, alongside medications that support blood clotting to stabilize the dog.
Supportive care is important for managing DIC. This includes close monitoring and adjusting treatment based on the individual response. The goal is to prevent further clotting and manage any bleeding issues effectively.
Management
Effective management of DIC involves intensive monitoring and supportive care in a veterinary clinic. Each dog’s treatment must be tailored to their response, ensuring optimal care and reducing complications.
Regular check-ups and continuous observation are key to managing the progression of DIC. Medication and therapy changes may be necessary, depending on the dog’s condition and any underlying issues.
Prevention
Preventing DIC requires managing and treating underlying conditions promptly and effectively. Early detection and intervention can prevent the coagulation cascade from starting.
A healthy lifestyle can play a significant role in prevention. A balanced diet, regular exercise, and stress reduction help support overall health and reduce the risk of triggering DIC.


