Name:
Polymyositis
Other Name(s):
Acronym(s):
Severity:
Genetic:
Idiopathic:
Predisposed Breeds:
Onset Age:
Overview
Polymyositis is an inflammatory muscle disease affecting dogs. It involves the widespread inflammation and degeneration of skeletal muscles, causing muscle weakness and pain. Although polymyositis is an uncommon condition, its severity can vary significantly among affected dogs. Some breeds, including German Shepherds and Labrador Retrievers, show a genetic predisposition to this condition.
Causes
The primary cause of polymyositis is believed to be an autoimmune response, where the dog’s immune system attacks its own muscles. This misdirected attack results in inflammation and muscle fiber damage, leading to weakness.
Secondary causes can include systemic diseases or infections that provoke an immune response, potentially triggering polymyositis. These conditions may exacerbate the immune system’s attack on muscle tissues.
Genetic predispositions and environmental factors may also contribute to the development of polymyositis. While these factors are not well understood, they may play a role in the disease’s onset.
Predisposed Breeds
Breeds predisposed to polymyositis include:
Symptoms
Primary symptoms of polymyositis include generalized muscle weakness and difficulty swallowing. Exercise intolerance is also common, as affected dogs struggle with physical activities.
Secondary symptoms may involve muscle pain and lethargy because of muscle atrophy. Weight loss can occur if the condition leads to significant muscle degeneration.
Other symptoms of polymyositis can include fever and depression. In severe cases, respiratory difficulties may arise if the muscles involved in breathing are affected.
Polymyositis symptoms include:
- Generalized muscle weakness
- Difficulty swallowing
- Exercise intolerance
- Muscle pain
- Lethargy
- Weight loss
- Fever
Diagnosis
Diagnosing polymyositis requires a thorough clinical examination. Veterinarians typically conduct blood tests to check for elevated muscle enzymes, which indicate muscle damage.
Electromyography may assess the electrical activity of muscles. A muscle biopsy can confirm inflammation and degeneration, distinguishing polymyositis from other conditions.
Polymyositis should be differentiated from other diseases, like myasthenia gravis, dermatomyositis, and infectious myositis. Correct diagnosis is important for effective treatment.
Treatment
Treatment for polymyositis often involves immunosuppressive medications, such as corticosteroids, to reduce muscle inflammation and suppress the immune response. These medications help manage symptoms and prevent further muscle damage.
Sometimes, additional therapies may be necessary. Physical therapy can maintain muscle strength and improve mobility in affected dogs. Regular veterinary check-ups ensure proper management of the condition.
Management
Long-term management of polymyositis includes regular veterinary check-ups to adjust medication dosages as needed. This monitoring helps control the condition’s progression and maintain your dog’s quality of life.
Physical therapy plays an important role in managing polymyositis. It helps maintain muscle strength and flexibility, which is essential for dogs with muscle weakness and atrophy.
Prevention
There is no known prevention for polymyositis, but early detection can significantly improve outcomes. Regular veterinary check-ups and awareness of early symptoms are important.
Maintaining a balanced diet and healthy lifestyle may support overall well-being, although they do not prevent polymyositis. Early intervention remains the best approach to managing this condition effectively.


